112 years of SIXT. 112 years of tradition.
Car rental in Panama
Cars
Trucks
Different return location
Pick-up date
Return date
Airport, city or address

Car rental in
Panama

4.3
Our customers love us
4.3 stars from 497 reviews in Panama.
Easy pickup and returns
Our 3 SIXT Panama airport locations make renting a car hassle-free.
More flexibility
Change or cancel bookings at no extra cost at most of our locations worldwide.

Places to start your journey in Panama

Our top branches in Panama

4.0
Tocumen International Airport
Via Tocumen 1
0831-02510 Panama
Panama
4.1
Panama Pacifico Airport
Avenida Mulvehill
0831-02510 Panama
Panama
4.6
David Airport Enr. Malek
Mayor Patricio Janson 001
0831-02510 David
Panama

Discover Panama

Car Rental in Panama

Car rental in Panama is made easy when you choose SIXT. We offer plenty of locations in Panama including those in urban centers like Panama City, and at major airports. Our branches offer convenient hours, with some locations offering 24-hour service. You can choose from a vast range of car categories and find something to meet your needs. Our branch staff also speaks English to better assist you with your rental. If you have bulky items to haul on your trip, choose a pickup truck. Or if you are traveling with a group, book a roomy passenger van.

SIXT Services in Panama

For those in need of car rental in Panama, SIXT is the answer. When you rent a car in Panama with us, you can choose from a variety of car categories including compact cars, sedans and SUVs. Add prepaid fuel to your rental to save time and money. Or add GPS and an additional driver to make your trip more comfortable. Whether you need a one-day rental or a weekly rental, SIXT is ready to meet all your rental car needs.

Best places to visit in Panama

  • Panama Canal: This is certainly one of the most famous landmarks in Panama and known throughout the world. The canal makes its way from Panama City on the Pacific Ocean to Colon on the Caribbean Sea. This marvel of engineering is a must-see for visitors.
  • Panama City: This is the largest city in Panama, and its capital. It is quite often regarded as one of the most modern cities in Central America and in fact many people refer to it as the Dubai of Latin America. Visitors here will find all manner of luxury shopping malls, high-end resorts and magnificent skyscrapers dotting the landscape.
  • *Bocas del Toro: *This is a cluster of islands and keys that sit between Amarante Bay and Chriqui Lagoon on the Caribbean Sea. This is a great place to do some exploring via either water taxis or private boats. In addition, Isla Colon offers access by ferry or plane. Explorers in this area will find several wild jungles and national parks with all manner of plant and animal life to see.

Winter in Panama

Because Panama offers such an amazing climate year-round, this is a great place to escape cold winter months in other parts of the world. This is a great time of the year to try out some of Panama’s many golf courses. Other activities that you can take part in during the winter include sport fishing, snorkeling, tours of the rainforest and even white-water rafting.

Customer reviews & feedback

4.3
4.3333335
Based on 497 reviews
from our Customer Excitement Score survey*

What our customers are saying

4.7
Vehicle handover
4.6
At the SIXT branch
4.5
Vehicle return
Sixt W.
5.0
good job keep it up
Bryon W.
5.0
We rented a car at the Tocumen location for the month of March 2019. Our contact (Martin) helped us through some booking difficulties and was very helpful and understanding when we had some mechanical problems. I would like to thank Martin for his help and being available when we needed him. Mucho gracias from Canada.
Eryn B.
5.0
We had a great experience with Sixt at Tocumen and would recommend. Specifically, staff at the check-in desk was really informative and helpful, and gave us great tips for our trip. I appreciated that Sixt includes the insurance in the price and that pricing felt very transparent overall. The contract does mention the large deposit but that should be more clear; it seemed to be the biggest complaint in other reviews. Overall, we had great service and felt we got a good price for the rental. I would definitely recommend and use Sixt again.

*Our Customer Excitement Score is based on a survey sent to all customers who booked in Panama. The score is an average of all customer responses.

Good to know when renting in Panama

Accepted payment methods

We accept all major credit cards in the renter’s name. Prepaid and debit cards as well as cash cannot be used for payment.

One-way car rental in Panama

We allow one-way rentals between SIXT stations in Panama, depending on the rate. An additional fee may apply.

Cross-border travel

You are not allowed to take your SIXT rental in Panama into neighboring countries.

Select the Pay on Arrival booking option and cancel your reservation free of charge if you need to.